- "Happy Fourth of July, Packie."
- ―Francis to Patrick McReary
For Fourth Of July, the McReary family are having a party at their house, and Francis is planning to launch some fireworks at night to celebrate the holiday. Meanwhile, Salvador is still upset because of Kate breaking up with him in the previous comic and getting back with her ex-boyfriend Mark Sanders.
♥ = character's debut
♠ = character does not speak throughout comic
♣ = character is mentioned only
♦ = character appears in a speaking/non-speaking cameo only
- Patrick McReary
- Francis McReary
- Gerald McReary
- Derrick McReary
- Kate McReary
- Maureen McReary ♦
- Angel Chacon
- Salvador Real
- Eduardo Tena ♠
- Claude ♠
- Tony Gonzales
- Salvador Martinez
- Pablo Torres
- Zalma Torres ♦
- David Saldivar ♦
- Mark Sanders
- Daniella Spencer ♣
- Drew Brees ♣
- This is the last comic where Maureen appears as a widow in.
- This is the fourth holiday-themed comic of the series. ("The McRearys' Halloween Special!", "Happy New Year!", " Love is What Makes the World Go 'Round")
- The events of The Pool Date were mentioned in this comic. Also, flashbacks of "Happy New Year!", " Love is What Makes the World Go 'Round", and "The Pool Date" were shown in this comic.
- Third time Packie and Francis throw a party. ("Happy New Year!", "House Party")
- Sixth comic to remain at night for the entire comic. ("The Curse of the Milderbeast", "The McRearys' Halloween Special!", "Happy New Year!", "House Party")
- Eduardo appears in this comic but does not speak.
- This comic is similar to "Happy New Year!", both comics take place at night, involve the siblings throwing a party, and have a scene with Salvador at Kate, with Mark Sanders involved.
- This is Pablo and Zalma's first speaking role since Field Trip Gone Wrong!, and David's first speaking role since Not Afraid (Of Losing My Concert Tickets).
- This comic was released the day before the series' two year anniversary in 2015 (being released on July 7).