- "We'll see who Packie likes the most!"
- ―Gerald McReary
Best Brother is the ninth comic in Season 2 of Sibling Rivalries, and is the 19th comic overall.
♥ = character's debut
♠ = character does not speak throughout comic
♣ = character is mentioned only
♦ = character appears in a speaking/non-speaking cameo only
- Patrick McReary
- Francis McReary
- Gerald McReary
- Derrick McReary
- Kate McReary ♦
- Maureen McReary ♦
- Salvador Real
- Eduardo Tena
- Claude ♠
- David Saldivar ♦
- Joel Gonzales ♦
- Braulio Guillen ♠
- Armando Vasquez ♠
- This is the first comic to actually feature a sibling rivalry (Francis, Gerry, and Derrick fight to see who Packie likes the most), while all previous comics have no rivalries, making the series title odd.
- The way Salvador falls after being hit by a paintball headshot is similar to the old death animation from GTA III-GTA Vice City Stories.
- The title is a reference to the 2011 Nickelodeon movie Best Player.
- It's revealed the McRearys and their friends have paintball gun fights, with the guns being based on GTA weapons.
- This is the first comic after "The Big Trade-Off" which Angel Chacon is absent in.
- Third time Joel Gonzales appears without James Johnson after the comic "Gonzales Vs. McReary". ("The Curse of the Milderbeast", "San Salvador's Story")
- At the end of the comic, Salvador indirectly mentions Armando Vasquez and Braulio Guillen from Sibling Rivalries: Salvador Real's Adventures.
- Thia marks the first series appearance of David Saldivar after appearing in SR: SRA, although in this comic he is only referred to as D to avoid revealing too much about him; the next comic properly introduces him.